Phytochemical Study of Endemic Species Helleborus Caucasicus and Helleborus Abchasicus

Medea Beridze, Aleko Kalandia, Indira Japaridze, Maia Vanidze, Natela Varshanidze, Nazi Turmanidze, Ketevan Dolidze, Inga Diasamidze, Eteri Jakeli


The floristic region of Adjara represents the "Hotpoint" of Caucasians, which is distinguished by the uniqueness of its relict Colchis flora. It represents one of the most powerful refuges in western Eurasia, which is not touched by the chill because of its special geographical location. 176 endemic plants are spread in southern Colchis, of which 45 can be used for some medical treatments. The bioecology and detailed phytochemical content of some medicinal plant populations have not been studied so far. The research objective is to study the phytochemical content of endemic species of Helleborus Caucasicus and Helleborus Abchasicus that have spread in southern Colchis. The research method for the phytochemical content included the separation analysis, which was performed using UPLC-MS (Waters Acquity QDa detector). Three Steroidal glycosides were isolated from the MeOH extract of the plants of Helleborus Caucasicus and Helleborus Abchasicus: Hellebrigenin-D-glucose, 20 – Hydroxyecdysone and Hydroxyecdysone – 3 glucoside. Three Steroidal glycosides and Hydroxyecdysone -3 glucoside have been isolated from the MeOH extract of Helleborus Caucasicus.


Doi: 10.28991/HIJ-2020-01-01-04

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Phytochemistry; Bioecology; UPLC-MS; Helleborus Caucasicus; Helleborus Abchasicus.


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DOI: 10.28991/HIJ-2020-01-01-04


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